Obesity and Treatments
December 7th, 2011 | Published in Sexual Health

New medications are currently produced and introduced to the market to cater for the imposing obesity ailment in humans… The medications are in fact of herbal origin; extracts of plant parts and the purified active principles, which are presented in the form of pills, drinks, ointments and gels, with the view of reducing the body fat through excessive burning or undue release.
The slimming effects are successful in many cases, though the goal can be achieved through regular and moderate feeding with low calorie food and strenuous body exercise.
Overweight and obesity is related to an aggregate of technological, social, economic and environmental changes, including increase in sedentary activities, such as radio listening, TV watching or simply lazing about.
Obesity literally means that the body fat has accumulated to more than 25-33 % of the average content in a healthy body, and may lead to reduced life expectancy. It is also associated with diverse diseases such as heart disease, type 2 diabetes, cancer, hypertension, hiperlipidema, osterioarthertis as well as difficult breathing. Child obesity is often carried over into adulthood and may be difficult to treat later.
Obesity also increases the risk of death in current or former smokers as opposed to non-smokers. The increase in the body fat induces insulin resistance in diabetic persons, and increases the risk of thrombosis.
Anti-obesity drugs will help to reduce the appetite, or inhibit fat absorption. However, surgery may be necessary in certain cases so as to reduce the stomach volume or bowel length. This will inherently reduce the ability of absorbing nutrients from consumed food.
However, some people have a family tendency to gain weight through genetic factors which explain the dramatic increase in rates of overweight and obesity.
There are cases where both of the above treatments may not be successful, when obesity is endemic through gene expression. This kind of malicious kind of obesity cannot be strained through either bodily exercise or excessive intake of slimming action medications.
Now, recent evidence has led to the discovery of a gene , Ad-36,called E4OBF-1.which causes precursor cells to differentiate into fat cells, and hence promotes obesity in humans as well as animals.. The viral gene is said to be responsible for triggering this process. When the expression of the E4 ORF-1 is blocked in cells infected by Ad-36, the cells failed to differentiate into fat cells. This is a proof that this gene is both necessary and sufficient for fat cell differentiation.
It is hoped that one day, researchers may be able to block E4 ORF-1 in humans to prevent Ad-36-induced obesity.
The gene also makes cells more responsive for insulin, in which drugs that mimic this part of the gene’s action may be useful in treating type 2 diabetes.
In spite of this genetic factor, one has to continue, through medication and exercise to fight it off, in at least to keep thing steady
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